Gender-specific expression of complex-type N-glycans in schistosomes
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چکیده
منابع مشابه
Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans.
Dimeric galectin-1 (dGal-1) is a homodimeric lectin with multiple proposed functions. Although dGal-1 binds to diverse glycans, it is unclear whether dGal-1 preferentially binds to specific subsets of glycans on cell surfaces to transmit signals. To explore this question, we selectively inhibited major glycan biosynthetic pathways in human HL60, Molt-4, and Jurkat cells. Inhibition of N-glycan ...
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hibit flexibility with respect to the rigid core. Surprisingly, similar studies on the a ( 1-3) arm of ‘bisected’ sugars from rabbit IgG (see below) and sialylated oligosaccharides isolated from bovine prothrombin (D. L. Fernandes, unpublished work) which contain a GalB(1-3)GlcNAc linkage in the outer chains show similar NOE effects when compared to the ‘complex’ oligosaccharide from human sero...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2006
ISSN: 1460-2423,0959-6658
DOI: 10.1093/glycob/cwl020